Cell Separation

Cell separation is the process to enrich a specific cell population such as CD3 positive Lymphocytes, CD14 positive Monocytes or CD19 positive B-Cell directly out of whole blood you have the option to use positive or negative (depletion) selection. Actually both isolation methods are antibody based. The antibodies recognize antigens (receptors) that the cells express on the surface. To support the enrichment the antibody can be coupled for example to other antibodies, fluorescent dyes or a solid phase.

pluriSelect offers products for positive isolation with the pluriBead system and negative isolation and depletion with pluriSpin system. Both technologies are without any magnetic beads

Cell isolation with pluriBead binds with specific antibody directly to the cells of interest. The cells will be "touched" by the target antibody. pluriBeads are detached after isolation.
pluriSpin method removes unwanted cells from your sample. The remaining cells of interest will be not touched. For example "B cell Enrichment" removes all cell types except B cells from the sample.
pluriSpin depletion removes specific cell type from the sample material. For example "Monocyte Depletion" means Monocytes will be removed from the sample material.
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  1. pluriSpin® Human CD4⁺ T Cell Enrichment
    pluriSpin® Human CD4⁺ T Cell Enrichment
    Helper T cells
  2. pluriSpin® Human CD4⁺ Cell Depletion
    pluriSpin® Human CD4⁺ Cell Depletion
    Helper T cells
  3. pluriSpin® Human CD8⁺ T Cell Enrichment
    pluriSpin® Human CD8⁺ T Cell Enrichment
    Cytotoxic T cells
  4. pluriSpin® Human CD8⁺ Cell Depletion
    pluriSpin® Human CD8⁺ Cell Depletion
    Cytotoxic T cells
  5. pluriSpin® Human NK Cell Enrichment
    pluriSpin® Human NK Cell Enrichment
    NK cells
  6. pluriSpin® Human NK Cell Depletion
    pluriSpin® Human NK Cell Depletion
    NK cells
  7. pluriSpin® Human B Cell Enrichment
    pluriSpin® Human B Cell Enrichment
    B cells
  8. pluriSpin® Human CD19⁺ Cell Depletion
    pluriSpin® Human CD19⁺ Cell Depletion
    B cells
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